| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Relative Telomere Length (RTL) |
Category |
Molecular Changes |
Affected targets |
Cardiac Aging |
Hallmarks |
Cellular Senescence |
Molecular |
DNA |
Description |
With each replicative cell division, telomeres will shorten, and this process has been correlated with cellular senescence. In addition to that, telomere shortening can be accelerated in the setting of disease conditions characterized by increased inflammation, which makes it a measurable marker of inflammation and oxidative stress. |
| EXPERIMENT INFORMATION | |
Region |
Lebanon |
Race |
multiple racial |
Samples |
502 |
Age |
18(over) |
Gender |
/ |
Application |
Predictive |
Conclusion |
Higher c-peptide level contributes to telomere shortening over time, suggesting that metabolic dysregulation may play a role in early aging. further understanding of this relationship and addressing high c-peptide levels can be important to prevent premature aging. |
Reference |
Mona P. Nasrallah, Front Endocrinol (Lausanne)., 2022 |
Details |
PMID:36060975 (Click to Pubmed) ； IF: ； Citation: |
Confidence |