| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Gut Microbiota |
Category |
Molecular Changes |
Affected targets |
Adipose Tissue Aging |
Hallmarks |
Altered Intercellular Communication |
Molecular |
RNA |
Description |
At the gastrointestinal level, aging entails the impairment of intestinal motility and increased permeability, as well as changes to the intestinal nervous system and associated alterations in GM |
| EXPERIMENT INFORMATION | |
Region |
Italy |
Race |
white |
Samples |
92 |
Age |
/ |
Gender |
/ |
Application |
Predictive |
Conclusion |
Overall, the main biomarkers associated with centenarians belonged to the verrucomicrobia phylum, including the akkermansia muciniphila species, considered to be a significant biomarker of gut homeostasis for its ability to promote intestinal integrity; at the same time, there is a significant increase in taxa with an anti-inflammatory phenotype, biomarkers of a state of health. this intestinal microbial ecosystem could guarantee intestinal health, which would then translate into the health of the whole organism. |
Reference |
Aldo Manzin, Nutrients, 2022 |
Details |
PMID:35745166 (Click to Pubmed) ； IF: ； Citation: |
Confidence |