| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Senescence-Associated Secretory Phenotype (SASP) |
Category |
Molecular Changes |
Affected targets |
Reproductive System Aging |
Hallmarks |
Cellular Senescence |
Molecular |
Protein |
Description |
We aimed to investigate the association of circulatory senescence-associated secretory phenotypes (SASPs) produced by senescent cells with chronological and menopausal age in women aged 45 years or more |
| EXPERIMENT INFORMATION | |
Region |
Asia |
Race |
yellow |
Samples |
76 |
Age |
67.6±6.6 |
Gender |
0/76 |
Application |
/ |
Conclusion |
Our findings demonstrate a positive association between select sasp proteins and age-related menopause and confirms that sasp proteins are a relevant physiological?in vivo?marker of aging among postmenopausal women. subsequent studies are needed for further evaluation of whether sasp indicators vary depending on the menopausal state and the potential exposures that induce those consequences. |
Reference |
Ok Hee Jeon, Rejuvenation Res, 2022 |
Details |
PMID:35583231 (Click to Pubmed) ； IF: ； Citation: |
Confidence |