| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Clusterin |
Category |
Independent Events |
Affected targets |
Pancreatic Aging |
Hallmarks |
Cellular Senescence |
Molecular |
Protein |
Description |
Clinical studies on the antisense oligonucleotide that targets clusterin (CLU) expression have been conducted and have shown efficacy in other cancers. |
| EXPERIMENT INFORMATION | |
Region |
Asia |
Race |
multiple racial |
Samples |
/ |
Age |
/ |
Gender |
/ |
Application |
Functional |
Conclusion |
We identified that clu inhibition leads to cellular senescence in pdac. our findings suggest that clu is a novel therapeutic target that contributes to the prognosis of pdac by inducing cellular senescence. |
Reference |
Suguru Mitsufuji, Ann Surg Oncol, 2022 |
Details |
PMID:35397747 (Click to Pubmed) ； IF: ； Citation: |
Confidence |