| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
CD8+ T effector memory RA cells |
Category |
Cellular Alterations |
Affected targets |
Hematopietic System Aging |
Hallmarks |
Altered Intercellular Communication |
Molecular |
Other |
Description |
terminally differentiated CD8+ effector memory CD45RA+ TEMRA cells and their subsets have characteristics of cellular senescence, accumulate in older individuals, and are increased in age-related chronic inflammatory diseases. |
| EXPERIMENT INFORMATION | |
Region |
worldwide |
Race |
multiple racial |
Samples |
140 |
Age |
/ |
Gender |
35/105 |
Application |
Anti-Aging |
Conclusion |
Our findings confirm the association of cd8+ temra and its subsets with cmv infection and provide a novel tool for their high throughput epigenetic quantification as a biomarker of immunosenescence. |
Reference |
Liina Tserel, Aging Cell, 2022 |
Details |
PMID:35397197 (Click to Pubmed) ； IF: ； Citation: |
Confidence |