| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Mitochondrial Energy Metabolism Markers |
Category |
Cellular Alterations |
Affected targets |
Skin Aging |
Hallmarks |
Mitochondrial Dysfunction |
Molecular |
DNA |
Description |
The decline of mitochondrial function throughout the lifespan is directly linked to the development of ageing phenotypes of the skin. |
| EXPERIMENT INFORMATION | |
Region |
Austria |
Race |
multiple racial |
Samples |
43 |
Age |
27.6±1.7)/76.2±1.73 |
Gender |
22/21 |
Application |
Functional |
Conclusion |
Overall, we demonstrate that ageing is associated with reduced protein levels of complex v of the mitochondrial respiratory chain and tfam. these alterations may impair essential mitochondrial functions, exacerbating the cutaneous ageing process. |
Reference |
Barbara Kofler, Experimental Dermatology, 2023 |
Details |
PMID:36851889 (Click to Pubmed) ； IF: ； Citation: |
Confidence |