| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Telomeric repeat-containing RNA (TERRA) |
Category |
Molecular Changes |
Affected targets |
Skeletal Muscle Aging |
Hallmarks |
Loss of Proteostasis |
Molecular |
Other |
Description |
it turned out that the C-rich strands of human telomeres are transcribed from very distal subtelomeric promoters by the RNA polymerase II, generating telomeric repeat-containing RNA (TERRA) molecules composed of subtelomeric sequences at their 5′ end followed by (UUAGGG)n repeats |
| EXPERIMENT INFORMATION | |
Region |
Belgium |
Race |
multiple racial |
Samples |
34 |
Age |
/ |
Gender |
36586 |
Application |
Functional |
Conclusion |
The age-dependent increase in terra expression might represent a novel biological marker of aging. |
Reference |
Louise Deldicque, Experimental Gerontology, 2021 |
Details |
PMID:34371098 (Click to Pubmed) ； IF: ； Citation: |
Confidence |