| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Grip Strength |
Category |
Physiological Characteristics |
Affected targets |
Skeletal Muscle Aging |
Hallmarks |
Loss of Proteostasis |
Molecular |
Other |
Description |
Grip strength is an overall indicator of general health status and an indicator of many specific health outcomes including cognition. Grip strength is a reliable marker of aging across the life course and predicts mortality and disability. |
| EXPERIMENT INFORMATION | |
Region |
UK |
Race |
multiple racial |
Samples |
27093 |
Age |
67/67/68/71 |
Gender |
12139/14954 |
Application |
Functional |
Conclusion |
We conclude that as the population ages, grip strength declines at a systematic and predictable rate equal to ?0.40 kg per year (approximately ?0.50 kg for men and ?0.30 kg for women) in residents of england aged 50 and older. age effects were predominant and most consistent across methodologies. while there was some evidence for cohort effects, such effects were minimal and therefore indicative that grip strength is a consistent physiological biomarker of aging. |
Reference |
Patrick O'Keefe, J Gerontol A Biol Sci Med Sci., 2022 |
Details |
PMID:34244743 (Click to Pubmed) ； IF: ； Citation: |
Confidence |