| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Bone Mineral Density (BMD) |
Category |
Histological Features |
Affected targets |
Skeletal Aging |
Hallmarks |
Cellular Senescence |
Molecular |
Other |
Description |
hip BMD decreased with aging in men and women |
| EXPERIMENT INFORMATION | |
Region |
Asia |
Race |
yellow |
Samples |
411 |
Age |
50-89 |
Gender |
203/208 |
Application |
Functional |
Conclusion |
This research was designed to create a cohort that more accurately reflects common residents. bmd decreased with aging in the femoral neck and total hip. on the other hand, there was no characteristic change with aging in the lumber spine. furthermore, all bone markers except for pentosidine and dpd showed no significant independent characteristics associated with age or gender in a multivariate analysis model. however, a significant association between low bmd and tracp-5b in females was observed; therefore, high bone resorption may be a factor for low bmd in female residents. |
Reference |
Hiroyuki Kato, Sci Rep, 2021 |
Details |
PMID:33837266 (Click to Pubmed) ； IF: ； Citation: |
Confidence |