| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Y-CpGs |
Category |
Molecular Changes |
Affected targets |
Reproductive System Aging |
Hallmarks |
Epigenetic Alterations |
Molecular |
Other |
Description |
Although DNA methylation (DNAm) variation of autosomal CpGs provides robust age predictive biomarkers, no male-specific age predictor exists based on Y-CpGs yet. Since sex chromosomes play an important role in aging, a Y-chromosome-based age predictor would allow studying male-specific aging effects and would also be useful in forensics. |
| EXPERIMENT INFORMATION | |
Region |
Netherlands |
Race |
multiple racial |
Samples |
1057 |
Age |
15-87 |
Gender |
/ |
Application |
Predictive |
Conclusion |
Overall, we introduce the first-of-its-kind male-specific epigenetic age predictor for future applications in aging research and forensics. |
Reference |
Manfred Kayser, Aging, 2021 |
Details |
PMID:33744870 (Click to Pubmed) ； IF: ； Citation: |
Confidence |