| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
DNA Methylation Age |
Category |
Molecular Changes |
Affected targets |
Adipose Tissue Aging |
Hallmarks |
Epigenetic Alterations |
Molecular |
Other |
Description |
DNA methylation (DNAm) age (mAge), a methylation biomarker for the aging process, might serve as a more accurate predictor of morbidity and aging status than chronological age. |
| EXPERIMENT INFORMATION | |
Region |
Israel, Germany, Denmark, USA and Austria |
Race |
multiple racial |
Samples |
120 |
Age |
/ |
Gender |
110/10 |
Application |
Predictive |
Conclusion |
Lifestyle weight-loss intervention may attenuate maging. deviation of mage from chronological age might be related to body fat distribution and glycemic control and could indicate biological age, health status and the risk for premature cardiometabolic diseases. |
Reference |
Iris Shai, Clinical epigenetics, 2021 |
Details |
PMID:33663610 (Click to Pubmed) ； IF: ； Citation: |
Confidence |