| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Gut Microbiota |
Category |
Others |
Affected targets |
Instestinal Aging |
Hallmarks |
Dysbiosis |
Molecular |
Other |
Description |
The gut microbiome affects many aspects of human health including aging and cancer. Recent evidence has demonstrated a causal relationship between the microbes in the gut and response to cancer treatment with immune checkpoint inhibitors (ICIs). |
| EXPERIMENT INFORMATION | |
Region |
Canada |
Race |
/ |
Samples |
/ |
Age |
/ |
Gender |
/ |
Application |
Functional |
Conclusion |
We review the potential mechanisms by which these effects occur and posit a model to interpret the broad-level changes observed. finally, we discuss trials currently underway to target this novel treatment modality in the understudied and growing older adult population. |
Reference |
Carolyn J Presley, Journal of geriatric oncology, 2021 |
Details |
PMID:33612452 (Click to Pubmed) ； IF: ； Citation: |
Confidence |