| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Telomere Length |
Category |
Molecular Changes |
Affected targets |
Lung Aging |
Hallmarks |
Telomere Attrition |
Molecular |
Other |
Description |
Several cross-sectional studies have related a shorter Telomere length, a marker of biological aging, with COPD outcomes. |
| EXPERIMENT INFORMATION | |
Region |
Spain |
Race |
/ |
Samples |
263 |
Age |
/ |
Gender |
222/41 |
Application |
Functional |
Conclusion |
This prospective study shows an association between accelerated telomere shortening and progressive worsening of pulmonary gas exchange, lung hyperinflation and extrapulmonary affection in copd patients. moreover, persistently shorter telomeres over this observation time increase the risk for all-cause mortality. |
Reference |
C Casanova, Respiratory research, 2021 |
Details |
PMID:33608013 (Click to Pubmed) ； IF: ； Citation: |
Confidence |