| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Cellular Senescence-Associated Genes |
Category |
Molecular Changes |
Affected targets |
Liver Aging |
Hallmarks |
Genomic Instability |
Molecular |
DNA |
Description |
The cellular senescence-related scoring system was validated as an independent prognostic factor and immunotherapy predictor for HCC, and patients with low CSS were characterized by prolonged survival time. |
| EXPERIMENT INFORMATION | |
Region |
China |
Race |
multiple racial |
Samples |
365 |
Age |
/ |
Gender |
245/120 |
Application |
Predictive |
Conclusion |
Our study confirmed the relationship between cellular senescence and immune cell infiltration, energy metabolism, chemokines, expression of immune checkpoint-related genes, and response to immunotherapy. |
Reference |
Shichun Lu, Sci Rep, 2023 |
Details |
PMID:36670201 (Click to Pubmed) ； IF: ； Citation: |
Confidence |