| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Brainstem Lesion |
Category |
Histological Features |
Affected targets |
Brain Aging |
Hallmarks |
Genomic Instability |
Molecular |
DNA |
Description |
Cohort 1 demonstrated that brainstem lesions were mostly associated with the mutation detection in CCM genes (brainstem, lateral temporal, and parietal lesions vs. lateral temporal and parietal lesions, AUC 0.928 vs. 0.779, P = 0.0389). |
| EXPERIMENT INFORMATION | |
Region |
South Korea |
Race |
multiple racial |
Samples |
21 |
Age |
35/39.8 |
Gender |
45517 |
Application |
Functional |
Conclusion |
The brainstem lesion could be the radiologic marker for fccm with the mutation detected. the age-related disease burden regarding fccm according to genetic information was demonstrated. |
Reference |
Kon Chu, Ann Clin Transl Neurol, 2023 |
Details |
PMID:36629374 (Click to Pubmed) ； IF: ； Citation: |
Confidence |