| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
DNA Methylation Age (Epigenetic Clocks) |
Category |
Molecular Changes |
Affected targets |
Instestinal Aging |
Hallmarks |
Epigenetic Alterations |
Molecular |
DNA |
Description |
Epigenetic clocks based on DNA methylation (DNAm) are a useful measure of the biological aging process with the potential to serve as a biomarker of an individual's susceptibility to age-related diseases such as CRC. |
| EXPERIMENT INFORMATION | |
Region |
worldwide |
Race |
multiple racial |
Samples |
334 |
Age |
19–81(58)/31–85(63)/28–79(57) |
Gender |
178/156 |
Application |
Functional |
Conclusion |
Individuals with a high risk for crc have epigenetic age deceleration in their normal colons measured by the phenoage clock, which may reflect a dysfunctional epigenetic aging process. |
Reference |
William M Grady, Clin Epigenetics, 2020 |
Details |
PMID:31900199 (Click to Pubmed) ； IF: ； Citation: |
Confidence |