| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Immunoglobulin G (IgG) |
Category |
Molecular Changes |
Affected targets |
Cardiac Aging |
Hallmarks |
Loss of Proteostasis |
Molecular |
Protein |
Description |
binding of autologous immunoglobulin G(IgG) to RBCs occurs at exposure times and stress levels found in cardiovascular devices and conclude that it may be a contributing factor to premature removal of red blood cells in patients with these devices. |
| EXPERIMENT INFORMATION | |
Region |
USA |
Race |
multiple racial |
Samples |
10 |
Age |
18–64 |
Gender |
/ |
Application |
Functional |
Conclusion |
Measurement of igg holds promise as a marker foreshadowing complications in cardiovascular patients and as a means to improve the design of medical devices in which rbcs are susceptible to sublethal trauma. |
Reference |
Edgar A O'Rear, Sci Rep, 2019 |
Details |
PMID:31857631 (Click to Pubmed) ； IF: ； Citation: |
Confidence |