| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Telomere Length |
Category |
Imaging Traits |
Affected targets |
Pancreatic Aging |
Hallmarks |
Telomere Attrition |
Molecular |
Other |
Description |
Knowledge of telomere biology may help distinguish malignant from benign radiographic lesions and guide risk assessment of these lesions. Peripheral blood samples were taken from 22 patients with suspected adenocarcinoma with the GGO radiographic presentation. Multidisciplinary discussion confirmed the need for surgery in all cases. |
| EXPERIMENT INFORMATION | |
Region |
Israel |
Race |
multiple racial |
Samples |
/ |
Age |
/ |
Gender |
/ |
Application |
Functional |
Conclusion |
In conclusion, patients with resectable early adenocarcinoma demonstrate abnormal telomere length and cell senescence in peripheral blood leukocytes compared to control subjects. abnormal telomere biology in the peripheral blood may increase suspicion of early adenocarcinoma among patients with ggo lesions. |
Reference |
Aliza Amiel, Thoracic cancer, 2019 |
Details |
PMID:30864244 (Click to Pubmed) ； IF: ； Citation: |
Confidence |