| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
B cell senescence-related genes in bladder cancer |
Category |
Molecular Changes |
Affected targets |
Immune System Aging |
Hallmarks |
Altered Intercellular Communication |
Molecular |
DNA |
Description |
Senescent B cells exhibit reduced antibody production and enhanced proinflammatory cytokine and chemokine secretion, exerting non-negligible functions in antitumor immunity. |
| EXPERIMENT INFORMATION | |
Region |
China |
Race |
/ |
Samples |
12 |
Age |
/ |
Gender |
/ |
Application |
Predictive |
Conclusion |
Collectively, a b cell senescence-related gene signature was constructed to evaluate the prognosis and immunotherapeutic response in blca, providing novel insights into the biological mechanisms. |
Reference |
Wanlong Tan, Functional & integrative genomics, 2022 |
Details |
PMID:36527532 (Click to Pubmed) ； IF: ； Citation: |
Confidence |