| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Taraxasterol |
Category |
Cellular Alterations |
Affected targets |
Cardiac Aging |
Hallmarks |
Cellular Senescence |
Molecular |
Other |
Description |
the function of cardiomyocytes decreases during aging, leading to changes in the functional and structural integrity of the heart, ultimately resulting in CVD. The decrease in the number of functional cardiomyocytes has a negative impact on cardiac function; thus, myocardial aging is one of the main factors that causes heart-related diseases (such as CVD). Therefore, alleviating cardiac aging is one of the main ways of treating aging-related cardiac diseases. |
| EXPERIMENT INFORMATION | |
Region |
China |
Race |
/ |
Samples |
/ |
Age |
/ |
Gender |
/ |
Application |
Functional |
Conclusion |
Taken together, this work illustrated that taraxasterol could reduce cardiac aging and fibrosis and enhance insulin signaling sensitivity, indicating that taraxasterol may be an effective drug or health food additive for treating cardiac aging and fibrosis. |
Reference |
Yongting Qin, Front Biosci (Landmark Ed), 2022 |
Details |
PMID:36472100 (Click to Pubmed) ； IF: ； Citation: |
Confidence |