| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Periostin |
Category |
Molecular Changes |
Affected targets |
Skeletal Aging |
Hallmarks |
Stem Cell Exhaustion |
Molecular |
Protein |
Description |
periostin (POSTN), also known as osteoblast-specific factor-2 , physiologically modulates ECM organization playing a unique role in the connection between the cells and the microenvironment that surrounds them and translates signals between ECM and cell. |
| EXPERIMENT INFORMATION | |
Region |
France,Monaco |
Race |
multiple racial |
Samples |
1096 |
Age |
74.96/76.35 |
Gender |
396/700 |
Application |
Predictive |
Conclusion |
Our study showed for the first time that increased plasma periostin levels were associated with declines in both physical and cognitive capacities in older adults over a 4-year follow-up. |
Reference |
Philipe de Souto-Barreto, Journals of Gerontology Series A-biological Sciences And Medical Sciences, 2023 |
Details |
PMID:36373873 (Click to Pubmed) ； IF: ； Citation: |
Confidence |