| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
Brain Waste Clearance Markers |
Category |
Histological Features |
Affected targets |
Brain Aging |
Hallmarks |
Epigenetic Alterations |
Molecular |
Other |
Description |
brain waste clearance such as perivascular spaces (PVS), of neurodegeneration such as brain atrophy, and of vascular disease, such as white matter hyperintensities (WMH). |
| EXPERIMENT INFORMATION | |
Region |
/ |
Race |
/ |
Samples |
1576 |
Age |
/ |
Gender |
/ |
Application |
Anti-Aging |
Conclusion |
Sleep impairments, and higher pvs burden, a marker of impaired waste clearance, were associated with faster loss of healthy white matter and increasing wmh in the 8th decade of life. |
Reference |
Joanna M Wardlaw, Sleep Med., 2023 |
Details |
PMID:37005116 (Click to Pubmed) ； IF: ； Citation: |
Confidence |