| BIOMARKER INFORMATION | |
|---|---|
Biomarker |
8-iso-prostaglandin F2α |
Category |
Molecular Changes |
Affected targets |
Eye Aging |
Hallmarks |
Other |
Molecular |
Other |
Description |
One of the major F2-isoprostanes, 8-iso-prostaglandin F2a (PGF2a), is formed during free radical-catalyzed peroxidation of arachidonic acid and is one of the most reliable biomarkers of oxidative stress in vivo |
| EXPERIMENT INFORMATION | |
Region |
Sweden |
Race |
multiple racial |
Samples |
516(258/258) |
Age |
71.2±6.9/71.2±6.8 |
Gender |
516/0 |
Application |
Functional |
Conclusion |
Systemic oxidative stress as measured by urinary f2-isoprostane, 8-iso-pgf2a, may be associated with increased risk of age-related cataract. |
Reference |
Alicja Wolk, Antioxid Redox Signal., 2014 |
Details |
PMID:24527727 (Click to Pubmed) ； IF: ； Citation: |
Confidence |